Background and objective: The present study provides valuable insights into the three-dimensional positioning of impacted maxillary canines and the associated mesiodistal dimensions of maxillary incisors in female patients. The objective of this study is to investigate the potential correlation between the displacement of impacted maxillary canines and the dimensions of the adjacent incisors. Material and methods: The sample consisted of pretreatment CBCT images of 28 females Yemeni, with palatal canine or buccal canine displacement (PDC or BDC) unilateral or bilateral, females with mean for aged 23.3± 2.1 years. An independent samples t-test was conducted to examine whether there is statistically significant difference between the means of two independent groups on two different variables. Results: The findings indicate that a significant correlation exists between the positioning of impacted canines and the dimensions of adjacent incisors. Specifically, patients with buccally displaced canines (BDC) exhibited larger mesiodistal crown sizes of maxillary incisors, suggesting a potential predictive marker for this type of canine displacement. In contrast, those with palatally displaced canines (PDC) demonstrated a significant reduction in incisor width, indicating a trend towards smaller tooth dimensions. This observation challenges the prevailing notion that spatial limitations are the primary cause of palatal impaction, as these cases often occur in individuals with adequate arch space. Conclusion: The contrasting incisor dimensions between the BDC and PDC groups underscore the importance of early morphological assessments in predicting canine eruption patterns. These insights can enhance diagnostic accuracy and inform individualized treatment planning in orthodontics, particularly for female patients who are more susceptible to canine impaction. Future research should further explore the implications of these findings on treatment outcomes and the underlying biological mechanisms influencing canine eruption.