Quality of Care and patient satisfaction are major challenges faced by the healthcare sector in Jordan. This paper aims to comparative study of the factors affecting service quality on the Patient Satisfaction from patient‟s perspectives in Jordan. Cross Sectional Survey. The study sample consisted of (200) respondents divided between King Hussein Medical Centre Hospital and Al-Bashir Hospital. The collected data were analyzed using the SPSS package. The study results revealed that quality of care has an impact on patient satisfaction. Moreover the results indicated that patients are satisfied with quality of care in the two hospitals. The study recommended that the two hospitals have to set up criteria for their quality provided for patients, and they are requested to provide sufficient number of qualifies medical staff to deal with the increased number of patients.