Diabetes is a common chronic metabolic disease that has attracted a lot of attention in the dental community because of its possible effects on peri-implant therapy. Dental implant procedures have grown in popularity as a means of replacing lost teeth. This systematic review aims to investigate the ways in which diabetes impacts different peri-implant therapy aspects. Up until February 2023, electronic databases such as PubMed, MEDLINE, and Embase were thoroughly searched. Eleven studies in total that complied with the inclusion criteria were included in the final analysis. These studies used both prospective and retrospective designs to investigate the impact of diabetes on implant outcomes. An overview of the impact of diabetes on the outcomes of peri-implant therapy, such as implant success, survival, and tissue health around the implants, is given in this abstract. Numerous studies repeatedly show that diabetes adversely affects these crucial facets of implant therapy. Diabetes affects soft tissue health around dental implants, lowers implant survival rates, and increases the risk of peri-implantitis.