Background: Diabetic foot ulcers (DFUs) are a serious complication of diabetes that can lead to amputation. Despite advances in prevention and treatment, early detection and intervention remain essential to improve outcomes. Objective: To review the latest evidence on the prevention and management of DFUs and wound care. Methods: A comprehensive literature search was conducted to identify relevant studies. Key findings were extracted and synthesized. Results: The best approach to preventing DFUs is one that is tailored to the patient's personal needs and risk factors. Comprehensive foot care is required, which includes regular examinations, education, and monitoring. Diabetes sufferers should also control their blood sugar levels, avoid smoking, and maintain a healthy weight. The best way to manage DFUs is likewise unique and relies on the degree and intricacy of the ulcer. Sharp debridement, unloading, dressings, antibiotics, and surgery are among treatment possibilities. Multidisciplinary care, comprising a number of healthcare providers, is frequently required to produce the best results. Treatment advances have resulted in considerable decreases in the risk of amputation and improved outcomes for DFU patients. Improved wound care treatments, new technologies, and a greater knowledge are among the advancements. Conclusion: DFUs are a serious complication of diabetes, but they are preventable and treatable. Early detection and intervention are essential to improve outcomes. By following the latest evidence-based guidelines, healthcare professionals and patients can work together to reduce the risk of amputation and improve outcomes for patients with diabetes.