The small saphenous vein (SSV) has several termination modalities and several types of afferent branches. The latter participate in the physiopathology of insufficiency of the small saphenous vein and explain the majority of recurrences after open or endovenous surgical cures. This study details the modes of termination and topography of afferents of the SSV. This is a cadaveric dissection involving 62 members of fresh and embalmed anatomical subjects. A popliteal approach and an extension is made towards the femoral region and towards the lateral malleolus are performed. Several parameters have been studied: the number of SSV, the number and distribution of terminal branches in the popliteal vein, in the great saphenous vein or in the thigh and the existence of musculocutaneous afferents of leg and thigh. We found that 45% of terminations were with a sapheno-popliteal junction. This form was absent in 55% of the cases. Consequently, the termination was either in the great saphenous vein, or in the posterior muscular compartment of the thigh, or in integumentary branches of the leg or thigh, or in the twin veins. This SSV received, in its course, twin veins, femoral veins, and integumentary veins.These anatomical variations of termination make a rigorous clinical and ultrasonographic examination indispensable in order to have a good mapping of the vein an to avoid recurrence of varicoses after surgery.