Twelve infants aged below six months were sampled from Women and Children Hospital of Ramadi, Iraq during the period April the 1st 2021 till October the 1st 2022. Infants were divided into two main groups; breast and bottle milk fed. Each group comprise three males and three females. Samples of feces were collected and lactobacillus specie were extracted. The extract was used once alone and another as a mixture with each of Amoxicillin, Amikacin and Cefixime antibiotics on petri dishes cultured with Staphylococcus, Klabsella and Psedudomonas bacteria. Diameter of inhibition was measure and resulted data were subjected to statistical analysis. The results of the statistical analysis showed that lactobacillus specie extract with the Cefixime has significantly highest mean diameter of inhibition compared to all other types of treatments. Infants who were on breast milk fed showed significantly better respond to the treatment than their counter part in the bottle milk fed group. Klabsella was found to respond weakly under almost all of the applied treatments.