Saudi Journal of Pathology and Microbiology (SJPM)
Volume-5 | Issue-06 | 315-318
Original Research Article
Histopathological Analysis of Bilateral Orchiectomy Specimens in Prostatic Adenocarcinoma
Dr. Farzana Siddiqui, Dr. S. P. Vyas, Dr. Q. Fatima
Published : June 11, 2020
Abstract
Introduction: Prostatic adenocarcinoma is one of the most frequently diagnosed cancer in adult males which seldom metastasizes to testis. Method: In current study the authors retrospectively analysed the 154 cases of bilateral orchiectomy done as hormonal ablation therapy in cases of prostatic adenocarcinoma. Result: We received a total 154 bilateral orchiectomy specimens of patients with prostatic adenocarcinoma in the period of three years. The Patients presented were from 42-86 year of age with a mean age of 60 years. In most (83.11%) of the cases testes were atrophied, 15.58% cases presented with normal histology and only two cases (1.30%) were reported positive for metastasis in testicles. Interestingly both of our cases also had a low PSA level. Conclusion: Testicular atrophy is the most common histopathological finding in patients of bilateral orchiectomy done for prostatic adenocarcinoma. Testicular metastasis is very rare but its possibility highlights the need for continued monitoring of patients with a history of prostatic cancer for local recurrences as well as metastatic disease. It also shows the importance of detecting metastasis to rare locations such as testicles specially in the setting of low PSA levels.