Background: Fibro-osseous jaw lesions are a group of tumours and proliferative disorders which present similar clinicopathological features. They comprise a range of developmental, reactive and neoplastic lesions characterized by replacement of normal bone by fibrous tissue, with subsequent formation of new mineralized tissue. Making diagnosis of fibro-osseus lesions may be challenging for clinicians and pathologists alike, owing to their overlapping clinicopathology. Objectives: This study aims to determine the pattern and clinicopathological distribution of fibro-osseous lesions of the jaws over a 7-year period. Methodology: This study retrospectively reviewed 90 fibro-osseous lesions diagnosed at the Oral Pathology laboratory of the department of Oral Pathology and Oral Medicine, Lagos State University College of Medicine, over a period of seven years (January 2013 to January 2019). Information regarding the type, frequency, age, sex and site distribution of FOLs were retrieved from the archival records of the Oral Pathology laboratory. Result: Fibro-osseous lesions (FOLs) of the jaws constituted 8.94% of all biopsies seen within the 7-year study period. Ossifying fibromas were the commonest FOL types accounting for 63.3% of all FOLs, followed by fibrous dysplasias at 20%. Lesions were observed within the age range of 9-72 years with an overall mean age of 31.9±15.5 years for all FOLs, 38.5±1.5 for Ossifying fibroma and 13.3±2.5 years for fibrous dysplasia. Female predilection for FOLs was recorded at a Male: Female ratio of 1:2.2. Mandible was the observed site of predilection for Ossifying fibroma, while the reverse was observed for Fibrous dysplasia. Conclusion: FOLs are relatively common jaw lesions, with ossifying fibromas occurring more frequently than others. Making an accurate diagnosis of FOLs in resource limited settings is greatly dependent on the availability of detailed clinical information, owing to their similar histopathologic appearances.