COVID-19 (Coronavirus disease 2019) is a highly contagious infectious disease caused by severe acute respiratory coronavirus 2 (SARS-CoV-2) in humans. It primarily spreads from person to person through respiratory droplets or by aerosols and less commonly by contact with infected surfaces or fomites. Pathologists and their technical staff can become exposed to potentially infectious patients and specimen. The current article provides a brief description of the current knowledge of the disease and the measures to be taken by the concerned health care workers to minimise their risk of contracting the virus during the ongoing pandemic.