Background: In India more than 50% of general hospital skin out-patient attendance consists of infections which are acute and usually recurrent like Scabies, Pyodermas, Superficial fungal infections, Parasitic and viral infections, Eczemas, Acne, Vitiligo, Pigmentary changes, Psoriasis, Lichen planus, Leprosy etc. The present study was therefore designed with the aim of studying the histopathological features of various skin diseases. So that, the clinicians can manages the case efficiently. Aims & Objectives: To find the clinicopathological correlation and to study the histopathological features of Non-neoplastic skin lesions. Materials & Methods: A total of 93 skin biopsies either Punch or Incision biopsies which were received in the department of histopathology were stained with Hematoxylin& Eosin, and studied microscopically. Results: Out of 93 cases, only 20 (21.5%) cases are not similar in clinical diagnosis and histopathological diagnosis but remaining 73 (78.5%) cases has similar diagnosis both clinicopathologically. Conclusion: histopathological study and comparing the clinical diagnosis serves as a very valuable diagnostic tool to understand and explain the pathology of various skin lesions.