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Saudi Journal of Pathology and Microbiology (SJPM)
Volume-5 | Issue-05 | 263-270
Original Research Article
Application of Bethesda Reporting System of Thyroid Cytology and Its Clinical Significance
Dr. Pooja Shrivastava, Dr. Farah Jalaly Meenai
Published : May 17, 2020
DOI : 10.36348/sjpm.2020.v05i05.007
Abstract
Final diagnosis of thyroid lesions requires morphological examination for which FNAC and histopathological examination become mandatory tests. In our study preoperative FNAC on 100 patients and along these histopathology reports of 22 patients were correlated and conclusions drawn after statistical analysis. Results: Diagnostic categorization of FNACs based on Bethesda classification showed that of the benign lesions (category 2), 45were Nodular colloid, 13Hashimoto thyroiditis, 13multinodular goitre, 3Primary hyperplasia and 2Hyperplastic nodule 1was of de-quervans thyroiditis, 1was of adenomatous goitre. Of the12 malignant lesions (category 6), 7were papillary carcinoma, 2anaplastic carcinoma, 1medullary carcinoma, 2 metastatic carcinoma on FNAC, 8 were suspicious for follicular neoplasm (category 4) and 1 was of follicular lesion of undetermined significance on FNAC (category 3). Among 100 cases, 22 were biopsied and subjected to histopathology. 11cases were benign. Out of these, 2 were of colloid goitre, 3follicular adenoma, 3multinodular goitre 2 was of hasimoto’s, 1 was of thyroglossal cyst. 11 cases were malignant, Out of these, 6 were papillary carcinoma, 3 were Follicular carcinoma and 1 medullary carcinoma 1 case of noninvasive follicular thyroid neoplasm with papillary like nuclear features. Out of 22 cases examined hitopathologically findings were similar to FNAC in 21 cases and findings differed in 1 case. The sensitivity & specificity for FNAC of thyroid neoplasm in present study were 82.6, 95.2%, respectively. Conclusions: FNAC is simple, safe & cost effective modality in investigation of thyroid swellings with high accuracy. The bethesda system of reporting has high concordance with the histopathological findings.
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