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Saudi Journal of Pathology and Microbiology (SJPM)
Volume-7 | Issue-12 | 473-479
Original Research Article
Clinical and Laboratory Profile in Children with Dengue Viral Infection: A Single Centre Experience
Dr. Hossain Sahid Kamrul Alam, Tania Fardush, Aumol Kanti Banik, Mohammad Rizwanul Ahsan, A.B.M Mahfuj Al Mamun
Published : Dec. 31, 2022
DOI : 10.36348/sjpm.2022.v07i12.006
Abstract
Introduction: Dengue is a major health problem affecting Bangladesh. The number of cases has increased over the last few years with a large number of populations being children. However data regarding dengue among children is limited. Aim of the Study: Aim of the study was to highlight the most common clinical features and hematological and biochemical findings of patients with dengue fever. Methods: This hospital-based observational study was conducted at the Department of Pediatrics of Dhaka Shishu Hospital, Dhaka, Bangladesh. The study was carried out from 15th May to 14th Octobar 2022 with 220 patients. Result: Total 220 children were enrolled in the study. There was a slight male predominance where male constituted 125 (56.81%) of the study group, while female was 95 (43.19%). That gave a male to female ratio of 1.18:1. Out of 44 cases of raised prothrombin time dengue fever consists of 14 (31.82%), 28 (63.64%) cases of dengue Fever with warning and 2 (4.55%) of severe dengue. In our study 26 (21.7%) cases had complication that was more common in age group of less than of 4 years (31.8%). In our study, complication of dengue was more common in dengue with warning sign (35.6%). In our study 44 (18.63%) cases have complication that is more common in age group of less than of (5-8) years. Conclusion: Hepatic involvement is more common in severe dengue associated with significant rise of liver enzymes. Hepatomegaly is the most important clinical sign but alteration of liver profile can occur with or without hepatomegaly.
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