Aims: To correlate AGE, TYPE, RBC INDICES in deciding the severity of anaemia in adult females in tertiory care hospital. Settings and Designs: A hospital based cross sectional study was done at our tertiary care centre in central clinical laboratory of Dr. D. Y. Patil Medical College & Hospital and Research Centre, Pimpri, Pune among 1000 adult females to evaluate prevalence of spectrum of anaemia. Considering a confidence level of 95% and confidence interval of 3.1 the number of patients in our study to achieve statistical significance is 999. This was calculated by Survey System (http://www.surveysystem.com/sscalc.htm#one). The Survey System ignores the population size when it is "large" or unknown. Population size is only likely to be a factor when you work with a relatively small and known group of people (e.g., the members of an association). Hence a sample size of 1000 was considered adequate for our study. Results: Majority of the females (42.44%) were in the age group of 26-35 years followed by 31.9% in the age group of 18-25 years, 19.2% in the age group of 36-45 years, 4.9% in the age group of 46-55 years and 1.6% in the age group of 56-65 years. 410 (41%) females had mild anaemia while 440 (44%) and 150 (15%) females had moderate and severe anaemia. The mean corpuscular volume (MCV) of females with mild anaemia was 70.94±1.35fl while the mean MCV of females with moderate and severe anaemia was 66.29±2.43fl and 60.82±1.77fl respectively. There was significant decrease in mean corpuscular volume (MCV) with increase in severity of anaemia as per ANOVA test (p<0.05). The mean corpuscular haemoglobin (MCH) of females with mild anaemia was 25.74±2.38pg while the mean MCH of females with moderate and severe anaemia was 21.16±2.07pg and 17.84±1.96pg respectively. There was significant decrease in mean corpuscular haemoglobin (MCH) with increase in severity of anaemia as per ANOVA test (p<0.05). The mean corpuscular haemoglobin concentration (MCHC) of females with mild anaemia was 32.76±3.14 while the mean MCHC of females with moderate and severe anaemia was 29.55±2.83 and 26.91±2.34 respectively. There was significant decrease in mean corpuscular haemoglobin concentration (MCHC) with increase in severity of anaemia as per ANOVA test (p<0.05). The mean red cell distribution width (RDW) of females with mild anaemia was 17.72±0.87% while the mean RDW of females with moderate and severe anaemia was 18.26±1.18% and 20.05±1.37% respectively. There was increase in red cell distribution width (RDW) with increase in severity of anaemia but the increase was statistically not significant as per ANOVA test (p>0.05). Conclusion: Iron deficiency anemia is increasing in females, specially in reproductive age group of developing countries. The haematological parameters can aid in early recognition of type and cause of anaemia and thereby improve the outcome. The study confirms that iron deficiency anaemia is the most common cause of anaemia in pregnancy and is a major health problem in developing and developed countries. Early detection, treatment and prevention of anemia can improve maternal as well as child outcome.