The most typical primary liver tumour, hepatocellular carcinoma, is becoming more prevalent. The two-gold standard curative treatment options are transplantation and surgical resection, but fewer than 20% of patients qualify as surgical candidates due to severe liver disease and/or co-morbidities. For the treatment of HCC that is inoperable, numerous interventional radiological techniques have been developed and thoroughly researched. The treatment of HCC currently heavily relies on interventional radiology. These methods have considerably aided in halting disease development in liver transplant candidates and extending survival in non-candidates. These medicines stand out for their low toxicity profiles, potent tumour response, and preservation of healthy hepatic parenchyma.