Introduction: In-hospital cardiac arrest is a common health problem associated with high levels of mortality, our goal is to identify the important elements that play a significant role in lowering cardiopulmonary resuscitation (CPR) in-hospital (code Blue) death rates. Methods: this was a retrospective cohort study, involving patients who had in-hospital CPR at Heraa General Hospital from January 2020 to June 2022. The data was collected from the hospital's information center. Results: our sample population was over 600 patients, selected randomly from the hospital's information center. Consist of 55.1% males and 44.5% of them were females with 53.9% having Pulseless Electrical Activity (PEA) as initial cardiac rhythm. The following variables: age, intubated before CPR, intubated during CPR, initial cardiac rhythm, Adrenaline 1mg, and Amiodarone 300mg showed P-valve less than 0.05. Conclusion: There is statistically significant association between the clinical variables: Intubated before CPR, intubated during CPR, initial cardiac rhythm, Adrenaline 1mg, Amiodarone 300mg and age and "Survived after Cardiopulmonary resuscitation (CPR)".