Saudi Journal of Pathology and Microbiology (SJPM)
Volume-5 | Issue-01 | 7-12
Original Research Article
Calculation of Bleeding Assessment Tool Score in all Patients of Bleeding Diathesis and its Correlation with Factor Assays: Experience in a Tertiary Care Centre
Dr. Vibha Gupta, Dr. Mansi Kala, Dr. Kunal Das, Dr. Vikas Shrivastava, Dr. Anuradha Kusum, Dr. Dushyant Singh Gaur, Dr. Meena Harsh, Dr. Neena Chauhan, Dr. Nadia Shirazi, Dr. Smita Chandra, Dr. Sushil
Published : Jan. 28, 2020
Abstract
Background: The congenital bleeding disorders haemophilia A and B are estimated to affect between one in 10 000 and one in 50000 males. The clinical profile of hemophilia patients is rarely reported in India. ISTH- Bleeding Assesment Tool score is one such score which not only helps us to diagnose a bleeding diathesis but may also help us in predicting the severity of bleeding potential of any patient with bleeding diathesis. Objective: To describe the clinical and epidemiological profile of hemophiliac patients in Uttarakhand. Calculate Bleeding Assessment Tool score in all patients of haemophilia and differentiate severe haemophilia from moderate haemophilia. Material and Methods: A total of 75 patients of all age groups with haemophilia A and B were included in the study. A detailed clinical history using ISTH -BAT along with clinical assessment by the hematologist was done. Special emphasis was laid on demographic details. Coagulation studies were done on STAGOSTA compact. Chi-square test was used for Assessing BAT scores. Results: The hospital based prevalence was 1.2% for haemophilia A and 0.3% for haemophilia B in our study. There were 74 % severe haemophilia and 5% of mild haemophilia in our study. The presence of inhibitors was 6%. There was significant statistical difference between the BAT score values of moderate and severe haemophilia (p value<0.05). Conclusion: The study suggested high prevalence of haemophilia in the state along with high numbers of inhibitors. More studies are required to establish the role of bleeding assessment tool in differentiating moderate haemophilia from severe haemophilia.