This article reviewed the contributions of Tertiary Education in Sub-Sahara Africa. It extols the impact of the global application of education in social, economic and political development in sub-Sahara Africa. The paper highlighted the Aims of tertiary education in sub-Sahara Africa such as Production of the much-needed high-level manpower essential for the nation’s growth and development, provision of centers of excellence in teaching, research and storehouses of knowledge for nurturing the manpower needs of the nation, promotion and encouragement of scholarship and community services, teaching and research and development. The Conceptual Links of the contributions of tertiary Education in sub-Sahara Africa were succinctly analyzed in the paper. Similarly, the Crux of Tertiary Education in sub-Sahara Africa was meticulously explained in the review. Some African Countries with concrete commitments to Tertiary education such as Burkina Faso, Burundi, Cameroon, Chad, Djibouti, Guinea, Madagascar, Malawi, Mali, Mauritania, Niger, Senegal and Uganda were showcased in the study. It further unveiled the Challenges of tertiary Education in sub-Sahara Africa such as inadequate funding, inadequate teaching staff, poor policy implementation, lack of resources, lack of information communication technology facilities, frequent labour disputes and closures of tertiary institutions, brain drain and poor leadership. The paper was recapped by putting forward the prospects to effective tertiary education in sub- Sahara Africa.