Osteomyelitis is an inflammatory disease which is heterogeneous in pathophysiology, clinical presentation and management. It occurs more commonly in the mandible than in the maxilla as the maxilla has a significant collateral blood flow, thin cortical bones which make it less prone to infection. Factors that predispose an individual to osteomyelitis of jaw is virulence of the microorganism, compromised vascular perfusion in the host bone at the local, regional or systemic level, and environment distressing host resistance or defense. Early diagnosis and management is of utmost importance so as to avoid the potentially serious consequences of the disease. We report an unusual case of maxillary osteomyelitis in a 33 year old female patient with poorly controlled diabetes and recurrent maxillary sinusitis