Background: The genetic diseases that are known to be accompanied with congenital malformations are often not well understood and has an element of surprise attached to it unless proved otherwise as seen in some familial cases. The raw emotions that run in the family of having a new guest, comes to a sudden halt. As the stakes are high and such cases should always be diagnosed as soon as possible a sincere attempt is being made in this study to understand the pre-natal diagnosis using the USG. Methods: Nine hundred twenty one patients records of scanning were observed out of which thirty patients who were diagnosed to have some malformations in USG scanning are reported. This study is done in the Department of OBG, Srinivas Institute of Medical Sciences, Mangalore. Results: Out of the observed 921 patients thirty was observed to have congenital anomalies. Conclusion: USG is able to detect the anomaly and is the gold standard for screening the patients