Saudi Journal of Pathology and Microbiology (SJPM)
Volume-4 | Issue-08 | 602-606
Original Research Article
PAP Smears and Acetic Acid Staining and Their Correlation with Histopathology – Original Research Article
Dr. D. Santhi Kiran
Published : Aug. 25, 2019
Abstract
The cervix is the most common site for genital tract infections and a target for viral, chemical carcinogens, which leads to
invasive carcinoma. Infections are the most common complaints in gynecological practice. With the advent of new drugs
for infectious diseases, the emphasis has moved to chronic diseases such as malignant diseases which are becoming
important cause of death. The objective of this study was to compare the visual inspection of acetic acid test qualities
with Pap smear and biopsy. Out of 500 cases, majority of the cases (232) were Negative for Intra-epithelial lesion or
malignancy (NILM), 126 cases were normal smears, 16 cases were Atypical Squamous Cells of Undetermined
Significance (ASCUS), 75 cases were Low-grade Squamous Intra-epithelial Lesion (LSIL), 37 cases were High-grade
Squamous Intra-epithelial Lesion (HSIL), 14 were carcinoma of the cervix. Pap smears are required not only for the
diagnosis and management of the malignant lesions but it is also helpful in identifying the infectious etiologies and
treatment in developing countries. They need to be correlated with histopathology for further management. In developing
countries, where it is not feasible to introduce pap smear screening of acceptable quality, VIA is alternative low cost
method for cervical screening.