Non traumatic liver rupture is an extremely rare condition; it most often complicates HELLP syndrome and rarely some liver diseases. We are reporting a case of 26-year-old man followed for behcet’s disease, presented to the emergency hemodynamically instable on a large hemoperitoneum due to a spontaneous liver rupture. We believe that intrahepatic hematoma was caused by a rupture of a segmental right liver artery aneurysm and then spontaneous rupture of the intrahepatic hematoma occurred leading to liver rupture. The surgical management consisted on perihepatic packing and two months later a medical management of sub infected liquefied residual liver hematoma