Background: Histoid leprosy (HL) cases are a reservoir of disease as it is a rare variant of lepromatous leprosy lead to further spread of leprosy. Therefore, early diagnosis and management of these cases needed to edadicate leprosy. The main objective of our present case series is to show different clinical features, histology findings and bacteriological findings in patients who attended tertiary care hospital outpatient department over last 6 years. Methods: It is a retrospective 6 year study (January 2014-January 2019). Particular of patients were obtained and clinical findings are noted in histoid leprosy patients in Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan (India). Results: In this study, there were 7 cases of HL. All cases were males in the age group ranging from 30 to 65 years with shorter duration of illness. 3 patients (42.80%) were de novo cases of HL. Nodule (71.5%) were the commonest skin lesions while arm (78%) were the most common sites involved.Earlobe infiltration was seen in 2 cases (28.5%). Lepra reactions were seen in one (14.2%) cases. No Deformity/disability were noted. Most common nerve involved was ulnar nerve. The bacteriological index (B.I) of Histoid leprosy, +3/ +4 were mainly seen in borderline leprosy (BB, BL), B.I +1/ +2 mainly in borderline tuberculoid (BT) leprosy. Conclusion: In this study majority of cases were de novo three out of seven.It also develop in patient who took inadequate or irregular treatment. So, early detection of Histoid Hansen is needed for awareness and to eradicate leprosy