Background: Anaemia is reduced oxygen carrying capacity of blood, due to reduced RBC mass and/or haemoglobin concentration [1]. Causes of anaemia include nutritional deficiencies, inherited genetic defects, medication-related side effects and chronic diseases. We had studied patients attending our tertiary care centre to determine aetiology of anaemia and its different clinical aspects during period of July 2012 to March 2014. Methods: A total 100 patients having anaemia were enrolled in the study and detailed clinical examination and relevant laboratory investigations were performed. Results: Out of 100 patients 55 were females and 45 were males. In present study 45 females fall in age between 12-40 years and 29 males were in the similar age group. Most common presenting symptoms were generalised weakness and easy fatigability. Pallor was noted in 94 patients. Severe anaemia (Hb <7 g/dl) were seen in 89% of the cases. 34% of the patients had subnormal serum iron levels and 45 patients were having low serum vit. B12 level (<187 pg/dl). Among other causes, 7 patients had anaemia of chronic disease, 4 had malabsorption and 2 had drug toxicity. Conclusion: Vitamin B12 deficiency in association with iron deficiency was found to be the commonest cause for anaemia in the study group. Haemolytic anaemia was more common in males in thid study