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Saudi Journal of Medicine (SJM)
Volume-4 | Issue-03 | 197-204
Original Research Article
Haemostatic Status in Uraemics in UNTH, Enugu
Chukwurah Ejike Felix, Obeagu Emmanuel Ifeanyi, Orjinta Rebecca Chinyelu
Published : March 30, 2019
DOI : 10.36348/sjm.2019.v04i03.007
Abstract
Uraemia is the clinical syndrome which occurs when there is a marked nitrogen retention due to renal failure. It had been suggested that urea level has an effect on coagulation and haematological profile. The haemostatic status was studied in Thirty known uraemic patients of the University of Nigeria Teaching Hospital Enugu. Fifteen non-uraemic people were used as controls. The mean result obtained are as follows:-Packed cell volume (PCV), 29 ± 5.4%, Platelet count, 238 + 80.4 n 109L, prothrombin time, 14.8 + 1.45 seconds, Bleeding time 5.9 + 1.98 minutes. For control subjects the following result were obtained: Packed cell volume40.8 + 2.4%, Platelet count 267 ±48 x 109L, Prothrombin time 12.9 +_0.93 seconds and Bleeding time 2.43 + 0.52 minutes. A statistical comparison of the above results between uraemic patients and control subjects showed that there were no significant difference in the platelet count (P>0.20) and prothrombin time (P>0.1) but showed significant difference in the packed cell volume and Bleeding time. A weakly positive correlation (r= + 0.11) was found to exit between prolongation of bleeding time and blood urea
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