In order to make full use of data of stroke and find the potential characters, we use computer algorithm to model the stroke so as to comply with the evolution of stroke disease. In order to visual express the complex reason of stroke, we use complex network to model the stroke so as to express the complex reason and describe the relation of stroke structure and function. Computer model and complex network model should be combined with stroke standard method and custom index, which are more direct for clinical index and practice. Hybrid methods for research of stroke are a test to model, prevention, control and serve for stroke and other clinical disease