Background: Breast diseases are showing a rising trend. The present study was conducted with aim of Clinicopathologic analysis of Breast Lumps. Materials & Methods: The present study was conducted on 130 breast specimens obtained from surgery department. The method of biopsy used was either open (excision and incision) or tru-cut needle biopsies depending on size and clinical parameters at presentation. Results: Maximum patients were seen in age group 40-60 years (70) followed by 20-40 years (40) and >60 years (20). Histological diagnosis was fibroadenoma in 49, fibrocystic disease in 20, benign phyllodes in 11, duct ectasia in 6, chronic mastitis in 15, granular cell tumour in 10, neurofibromas in 2, lactating adenomas in 4, lipomas in 6 and invasive lobular carcinomas in 22. Maximum masses were seen in upper inner quadrants (30%) followed by lower outer quadrants (24%), upper outer quadrants (12%), entire breast (11%), lower inner quadrants (10%), central (8%) and middle quadrants (5%). The difference was significant (P< 0.05). Conclusion: Most common breast mass was fibroadenoma followed by invasive lobular carcinomas. Most common site was upper inner quadrant.