Uterine fibroids, also known as uterine leiomyomas or fibroids, are benign smooth muscle tumors of the uterus. Most women have no symptoms while others may have painful or heavy periods. If large enough, they may push on the bladder causing a frequent need to urinate. Dermatoglyphics is referred to as study of the friction ridge formation that appears on the palms of the hands and soles of the feet. There have been works done by different researchers on dermatoglyphics in the field of medicine which has helped in the detection of diseases like breast cancer, anemia etc. But not much has been done at level 2 dermatoglyphics which has created a gap in literatures on those areas especially uterine leiomyoma. This study was aimed at determining the level 2 dermatoglyphic digital patterns in Uterine Leiomyoma. The study was non-experimental and analytical. One hundred subjects selected by simple random sampling. Chi-square test was done using SPSS twenty version. The result of the study has shown clearly that the most distributed level-2 pattern in both categories is the bifurcation and ridge crossing the least distributed pattern in both categories. In uterine leiomyoma the distribution of bifurcation was higher than in the control group. The higher distribution of bifurcations in the uterine leiomyoma could be attributed to the genetic difference in both categories. The difference between the uterine leiomyoma subjects and the control subjects (normal) was not significant statistically (p>0.05) in there pattern distribution, but there was a marked difference that can be used as a guide in the diagnosis of uterine leiomyoma condition