Lupus podocytopathy is a recently described phenomenon characterized by diffuse foot process effacement without peripheral capillary wall immune deposits and glomerular proliferation. It has been described in systemic lupus erythematosus patients with nephrotic syndrome in case reports and a few series. The term of lupus podocytopathy denotes that it as lupus nephritis-related phenomenon, however, the theory of coexisting minimal change disease is also a possibility. Each theory has its own supporting clinical and pathological facts. This literature review is made for a comprehensive analysis of the available clinical circumstances and histological data of the reported cases. Also, it elaborates on the pathological background for both diseases process. The aim of this review is to reach an optimum categorization of this phenomenon.