Saudi Journal of Pathology and Microbiology (SJPM)
Volume-4 | Issue-06 | 450-461
Original Research Article
Histomorphological Study of Mesenchymal Tumours of Uterine CorpusA Study of 492 Cases
Dr. Nischita Budihal, Dr. Jayashree G Pawar
Published : June 22, 2019
Abstract
Background: Difference between the benign and malignant counterparts of mesenchymal tumours is significant due to the
differences in the clinical outcome and the role of the surgical pathologist in making this distinction (especially in difficult
cases) cannot be underestimated.2 The aim of the current study is to evaluate the histomorphological features of
mesenchymal tumours of uterine corpus. Materials and methods: was undertaken in the Department of Pathology, JJM
Medical College, Davangere over a period of two years from July 2010- June 2012. Results: Out of the 492 cases, majority
were benign tumours accounting to 485(98.58%) cases, followed by 6(1.22%) cases of malignant tumours and one (0.20%)
smooth muscle tumour of uncertain malignant potential (STUMP). Conclusion: Differentiation between the benign and
malignant counterparts of mesenchymal tumours is through the use of multivariate criteria; that is, criteria that involves
several microscopic features such as differentiated cell type , presence and type of tumor necrosis, the degree of cytologic
atypia, the mitotic index, and the relationship to surrounding normal structures, including extrauterine sites. Morphological
features supported by proper usage of IHC markers will help in arriving at the final diagnosis.