Generally speaking, listening, speaking, reading and writing are four basic skills for English learners. Reading as a mean to learn English is indispensable in the process of English learning. Thus, English reading comprehension is especially important for English learners. However, grammatical metaphor in reading materials is always one of the reasons that cause troubles for English learners. Because of grammatical metaphors students may miss or misunderstand some important information in English reading materials. Thus, it is essential to conduct a deep research on grammatical metaphors. And this article will explore how interpersonal metaphors influence students’ English reading comprehension. This article will explore this kind of influence from two aspects: one is the Mood metaphors; the other is the Modality metaphors. In addition, some cases will be listed to support the ideas. Meanwhile, some feasible suggestions on English reading comprehension will be put forward