A novel family of macrocyclic complexes with tetra aza macro cyclic ligand and (X=Cl- , NO3-) have been synthesized and characterized by elemental analysis, IR, electronic, and EPR spectral studies. The molar conductance measurements of the complex in Dimethyl sulphoxide (DMSO)/dimethyl form amide corresponds to non-electrolytes for all the Mn(II) complexes except the complex with ligand LA which are 1:2 electrolyte. The spectra are consistent with the formula [MnLx2] and [Mn (LA) (H2O) 2] X2 and distorted octahedral geometry. The biological activity of these complexes was evaluated against different species of bacteria and plant pathogenic fungi and compared with different ligands.