Graphene, a carbon, displays unique 2-D structures with preternatural physical, chemical and electronics properties that necessitated its applications in different fields of engineering systems. Among these applications, bioelectronics application of graphene has attracted an increasing interest over the last years. The advantages conferred by the physical, optical and electrochemical properties of graphene-based nanomaterial have contributed to the current variety of ultra-sensitive and selective biosensor and sensors devices, Nano electronics, super-capacitors, solar cells, batteries, flexible displays, hydrogen storage in electronics. This paper provides a review on graphene variant properties and their applications especially in bioelectronics