Scholars International Journal of Biochemistry (SIJB)
Volume-2 | Issue-07 | 209-215
Original Research Article
Assessment of Hematological Parameters, Hematological Ratios and Serum Lactate Dehydrogenase Levels in Patients with Preeclampsia
Swetha Chandru, Rimsha Saleem F, Monalisa Biswas
Published : July 26, 2019
Abstract
Aim: To study haematological parameters, haematological ratios and serum total lactate dehydrogenase (LDH) levels in normal pregnant women and in women with preeclampsia. Materials & Methods: 30 women with preeclampsia and 30 normotensive pregnant women admitted to the Department of OBG were recruited for the study. Blood samples were collected and analysed for CBC, serum LDH and ALP in the Clinical Biochemistry & Pathology Laboratory of MVJ Medical College. Statistical tests were employed to evaluate the significance of the differences obtained between the groups. Results: Serum LDH and Neutrophil – Lymphocyte ratio (NLR) showed a significant difference between control group and preeclampsia group. Platelet count showed a negative correlation with systolic blood pressure and serum LDH levels and serum ALP showed a positive correlation with serum LDH levels in the patient group. Conclusion: These simple markers might be used as predictors of preeclampsia if analysed routinely in the third trimester of pregnancy. The study needs to be replicated with a larger sample size and prospective study design to validate the findings and implement these in clinical practice