Scholars International Journal of Biochemistry (SIJB)
Volume-2 | Issue-07 | 200-204
Original Research Article
Mqsga (Modified Quantitative Subjective Global Assessment) Scoring For the Assessment of Nutritional Status of Hemodialysis Patients and Its Correlation with Serum Albumin and Hs Crp (High Sensitive C-Reactive Protein)
Shubha Jayaram, Meghana N, Sahithya CS, Meera S, Hema NG
Published : July 29, 2019
Abstract
Malnutrition has been implicated as a possible indicator of development of atherosclerotic cardiovascular disease in hemodialysis patients. Recently a new quantitative scoring system, called MQSGA (Modified Quantitative Subjective Global Assessment) has been developed to assess dialysis malnutrition. Study was conducted with following objectives 1) To assess the nutritional status in hemodialysis patients by the MQSGA scoring. 2) To correlate the MQSGA score with biochemical marker of malnutrition- Albumin and inflammatory marker hs CRP (High Sensitive CRP). 50 patients in the age group of 20-70 years diagnosed as having chronic kidney disease undergoing hemodialysis were studied. MQSGA score was calculated using 7 features- weight change, dietary intake, GI symptoms, functional capacity, co-morbidity, subcutaneous fat and signs of muscle wasting. Serum albumin levels were estimated using end point colorimetric method and hsCRP using Immunoturbidimetric method. MQSGA scores in the present study was found to be 17.32+4.37 in males and 16.2+4.81 in females with a total 17.19+4.4. hsCRP levels was found to be significantly raised (16.59+21.4mg/L). Serum Albumin levels were low (3.27+0.67 g/dl), in both males (3.28+0.69) and females (3.22+0.153). There was a significant positive correlation between serum hsCRP levels and MQSGA scores of the subjects (p=0.0418, r=0.3156). To conclude Nutritional status of the patients undergoing dialysis is frequently ignored. Present study shows moderate degree of malnutrition in CKD patients. Simple methods of nutritional assessment and diet modification could have a favorable impact on the patient management.