Background: Presently snakebite has become a serious health problem in India.The actual incidence of mortality and morbidity related to the snakebite are not reported properly. Furthermore, the most neglected part is the long term endocrine dysfunction in survivors of russel viper envenomation. Materials and methods: Forty five survivors of russels viper bite patients were selected for the study according to inclusion and exclusion criteria. Admitted patients were treated accordingly and discharged in stable condition. The hormonal status were analysed and they have been followed up after 3 and 6 months. Results: Significant decrease in serum cortisol and prolactin were observed in survivors of russels viper bite patients particularly in those patients whose mean serum creatinine was more than 1.2 mg/dl and systolic blood pressure is more than 110 mm of Hg and diastolic Blood pressure is more than 70 mm of Hg. Conclusion: Measurement of long term hormonal status like serum cortisol and prolactin can be beneficial in survivors of russel viper bite patients.