Core needle biopsy (CNB) is a part of triple assessment for preoperative evaluation and diagnosis of breast cancer as it can distinguish benign and malignant lesion, insitu and invasive cancers. In addition to its primary role in establishing histologically diagnosis it can provide prognostic information like grade and type of tumor which can influence initial therapeutic decisions. We present the result of 80 patients of palpable breast lesion who underwent for core needle biopsy followed by therapeutic surgical excision. Diagnosis of lesion along with histological typing and grading of invasive carcinoma were determined in both core needle biopsy and excision and the result compared. We observed 83.2% agreement for histological typing. There was 66 % agreement with overall grade (kappa K value-0.56),71.2% for tubule formation score 66.6% for nuclear pleomorphism,55% for mitoses (component of Bloom Richardson grading).Only 45cases of grade 1 shows concordance but 80% of grade 3 cases show concordance between CNB and surgical excision. This result is of important clinical relevance as these are the patients potentially most likely to benefit from neoadjuvant therapy. The Major problem with assessing of grading of tumor on CNB is due to under sampling of most representative areas. Hence quadrant wise sampling with increase of attempts in different directions and assistance of image guidance would improve the accuracy of CNB.