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Scholars International Journal of Biochemistry (SIJB)
Volume-2 | Issue-02 | 26-30
Original Research Article
Reference Value for Uric Acid in Sudanese Healthy Adults
Sanna Alameen Aljak, Ibrahim A Ali, Omer A Musa
Published : Feb. 18, 2019
DOI : 10.36348/sijb.2019.v02i02.003
Abstract
Background: The final product of purine catabolism in human is uric acid. Serum uric acid is a balance between its production and excretion. The liver and intestine mucosa produce most of purine and also provided by diet. The kidneys eliminate two third of uric acid with the gastrointestinal tract eliminating one third. Objectives: The objective of this pilot study was to establish the normal values of serum uric acid in healthy adult Sudanese, males and females living in Khartoum state and compare the results with the international values. Methods: A cross sectional study was conducted during 2018 in Khartoum state on adult healthy males and females aged between 20 and 30 years as a pilot for the project.40 participants, 20males and 20 females, were assessed by a questionnaire covering age, medical history, physical activity, daily caloric intake and smoking history. Body mass index BMI was calculated by measuring weight and height by standard measuring device scales. A sample of 5ml venous blood was taken and measurement of uric acid was done. Results: The range of uric acid was: Males 2-5.7mg/dl and females 2- 4.5mg/dl. The international range of males is 3.4-7mg/dl and in females is 2.4-6mg/dl. Conclusion: The results of this study indicate that there is a difference in values of uric acid between international values and in Sudan, so the normal values for uric acid in Sudanese need to be established from a large sample.
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