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Saudi Journal of Pathology and Microbiology (SJPM)
Volume-4 | Issue-04 | 332-337
Original Research Article
Comparative Study of Bronchial Wash, Bronchial Brush Cytology and Bronchial Biopsy in Patients with Lung Malignancy
Dr. K. Mrudula, Dr. M. Anantha Satya Narayana, Dr. K. Rama Murthy, Dr. T. Asha
Published : April 30, 2019
DOI : 10.21276/sjpm.2019.4.4.10
Abstract
Early diagnosis of lung cancer plays a pivotal role in reducing death rate due to lung cancer. Bronchial washing, brushing and fine needle aspirations not only compliment tissue biopsies in diagnosis of lung cancer but also comparable. We aim to assess the diagnostic utility of bronchial wash and brush cytology and bronchial biopsy in diagnosing various pulmonary lesions and to compare the bronchial wash and brush cytology with bronchial biopsy in patients with lung cancer. All the patients who underwent fiberoptic bronchoscopy at Alluri Sitarama Raju Academy of Medical Sciences, Eluru during the period of August 2016 to June 2018 for suspected lung lesions on chest radiograph/ CT scan and came to cytology division of pathology department for bronchial wash & brush cytology were included in the study along with biopsy in available cases. Total 60 cases of bronchoscopically visible abnormal lesions underwent bronchial wash and/or brush cytology and/or bronchial biopsy. Of them, only 11.8% of cases of lung malignancy was detected by bronchial wash where as 28.9% of cases of lung malignancies were detected by bronchial brush and 58.8% of cases by bronchial biopsy. We conclude that endobronchial biopsies along with bronchial brush give better cellularity and yield when compared to bronchial wash. The probability of finding the histological subtypes is higher in Endobronchial biopsy when compared with brush and wash samples.
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