Acute appendicitis is one of the most common surgical cause of acute abdomen with life time risk of 7%. A 5-year study was conducted and it comprised of all the surgically resected appendices submitted to department of pathology, AlAmeen medical college, Bijapur. The study analysed various histopathological diagnoses, demographic profile and the rates of negative appendectomy. Total 777 cases were analysed, among them 392 were females and 385 were male, highest number of cases were seen in first and second decades of the life. It was found that acute appendicitis was more common in females and incidence of recurrent appendicitis is slightly higher in males. 18% of acute suppurative appendicitis was seen and 23 cases of acute eosinophilic appendicitis was noted. In present study, 25.7% of cases with faecolith in the lumen of appendix was noted. Parasitic infestation can cause blockade of the lumen leading to appendicitis. In our study only 2 (0.26%) cases had a parasitic infestation and enterobius vermicularis was the parasite identified in both the cases. The percentage of negative appendicectomy in our study was 5.15%. Negative appendicectomy was higher in females (62.5%) compared to males. Thus, in present study recurrent appendicitis was more common than the acute appendicitis, maximum number of cases were in the age group of first and second decades of the life, faecoliths considered very common cause of appendicitis was noted only in 25.7% and negative appendicectomy was more common among the females.