Once prescribed, within a hospital structure, the drug will follow a complex circuit, involving many intermediates, human and technical, and leading to the drug administration and its monitoring. From the point of view of pharmaceutical practice, the circuit is of course made of an important logistic part but also of a clinical part often underestimated but nevertheless essential to the safety of the patients during their stay in the hospital. In order to be able to combine the logistic and clinical aspect of the pharmaceutical activity in a hospital environment, it is essential to adopt an appropriate dispensing mode that allows to better secure the patient's medication management. The purpose of this article is to describe the practice of the nominative dispensing in hospital and to share the experience of introduction of this practice at the pharmacy of the Moroccan Institute of Oncology