Thyroid Dysfunction (TD) and Diabetes Mellitus (DM) are often found associated in the same patient and TD may affect the metabolic control of DM. TD is more prevalent in diabetics than in general population. The current study investigates the prevalence of TD in patients with DM, and explores its correlation with age, sex, type and duration of DM, and glycemic control (HbA1c levels). This was an observational, cross-sectional study of 212 patients with DM. All patients had undergone routine clinical and laboratory evaluations as per the standard clinical care. Medical data was collected and analyzed using Epi Info V3.5.4. Among the 212 DM patients evaluated, the overall prevalence of TD was 24.52%. The overall prevalence of TD was less in type-2 DM (T2DM; 24.46%) as compared to type-1 DM (T1DM; 37.5%); and slightly more in females (31.94%) as compared to males (28.65%). The prevalence of TD was high in the middle age (41-60 years) group (52.17%) as compared to other age groups. Subclinical hypothyroidism (SCH) was the most common type of TD (11.79%) with maximum prevalence (50%) in T2DM. Patients with DM reported a high prevalence rate of 24.52% for TD. Patients between 41-60 years of age had higher prevalence of TD. Prevalence was slightly more in more in females as compared to males. Our data suggests for screening of DM patients for risk of TD that might be helpful in secondary and primary prevention and possible better metabolic control