Paederus dermatitis is a type of irritant contact dermatitis caused by beetles of the Paederus species. The objectives of this study were to know the incidence, clinical varieties, histopathological changes, and microbiological findings. Methods: 100 patients of Paederus dermatitis were considered, a detailed history was taken and a general examination was done. Skin biopsy and skin swabs were taken from all the patients and findings were noted. Follow-up was done to know the prognosis of the patients. Results: The study showed that males were more frequently affected than females with a ratio of 3:2, most prevalent in the months of March and September. Itching and burning were common symptoms with the majority of the lesions appearing on uncovered areas of the body. The most common lesions seen were erythema, vesicles, and erosions. Different stages of the lesions showed different histopathological changes with epidermal necrosis, dermal edema, and lymphocytic infiltrate being most common. Hyperpigmentation was a common complication which could be avoided if treatment is taken in the early stages. Conclusion: Pruritus was the predominant complaint in the patients with burning sensation being present in almost equal numbers. Hyperpigmentation was the main complication which was long-standing if the patients did not initiate treatment in the early stages of the disease. Use of preventive measures against the beetles along with prompt treatment reduces the complications and improves the quality of life for the patient.