Saudi Journal of Pathology and Microbiology (SJPM)
Volume-4 | Issue-03 | 258-263
Original Research Article
Clinico-Histopathological Correlation in Hansen’s Disease
Dr. S. Srismitha, Dr. S. Karthik, Dr. B. Shobana, Dr. S. Manjani
Published : March 31, 2019
Abstract
Aim: The aim of the present study was to perform clinico-histopathological correlation of skin lesions in all patients with
a clinical suspicion of Hansen’s disease. Materials and Methods: A 3 year retrospective study from 2016-2018 was
carried out with all the clinically suspected cases of Hansen’s disease along with histopathological examination of skin
biopsies. Results: Out of the 60 cases diagnosed as Hansen’s disease, majority belonged to age goup 31-40 years with a
male preponderance. Most number of cases diagnosed were of Borderline tuberculoid type (24/60). Overall clinicohistopathological correlation was 58.3%. Maximum correlation was evident at the polar ends of the spectrum with a
slightly better correlation for lepromatous leprosy (75%). Conclusion: Correlation between clinical and histopathological
features is required for accurate classification of Hansen’s disease. Clinical detection and histopathological diagnosis of
borderline lesions remains challenging and hence the need for interpretation along with the clinical findings.