This is a cross sectional study of 60 patients with organophosphorus poisoning admitted at MGM Medical College and Maharaja Yashwantrao hospital Indore from June 2013 to May 2014. Severity of poisoning and requirement of ventilator support were studied in these patients. The POP scale and pseudo cholinesterase levels both showed a significant association in predicting the need for ventilatory support. Lower grade of poisoning had a better outcome whereas higher severity of poisoning had a poorer outcome