This study investigated the prevalence of Canine Distemper (CD) Antigen in dogs in three major clinics in Northern part of Plateau State. A total of 150 blood samples were and sera were used to test for CD Antigen using Rapid CDV Ag Test Kit which is a chromatographic immunoassay for qualitative detection of Canine Distemper Virus (CDV) antigen. Associations between factors were analyzed using Chi square at 95% confidence interval. A prevalence of 45.33% was recorded. There was significant difference in relation to age, breed and vaccination status (P<0.05) but no significant difference in relation to sex and location. The result of the study established the presence of CDV infection in the study area incriminating age and breed as the risk factors. Therefore, there is need for establishment of adequate control measures especially through vaccinations and sero-monitoring of the vaccinated animals in the area using rapid CDV test kits.