Abstract: The antimicrobial resistance among gram negative bacteria is increasing among patients, community and healthcare workers. Determination of these species and their resistance profile is mandatory for successful empiric antibiotic therapy. The aim of the current study was to investigate the prevalence of drug resistant gram negative isolates from community and healthcare workers in Iran. A total of 10 previous published studies were found while searching internet searching engines including PubMed, Google scholar, Sciverse, and so on. The key words of “gram negative”, “drug resistant”, “healthcare workers”, “community” and “Iran” were searched in the noted searching engines. The publications related to the healthcare, patients and hospital settings were excluded from the study. Moreover, healthcare workers of children and adults/ageing and in addition, community settings were included in the study. Data were analyzed with Exel software. Among the published studies, most of bacterial species among healthcare workers and community were in Enterobacteriacea family, mostly E. coli (3.75%) and K. pneumonia (3.74%), A. bumanii (3%), P. aeruginosa (1.25%), E. aerugenes (1.2%), Proteus spp (0.1%) and other species. Two publications were about caregiver’s mobile phones and 2 were associated with hands. Moreover, community and workers hands were more contaminated than phone and coats. The results showed that community and healthcare workers can play a role in contamination spread. Hands of healthcare workers were the highest level of contamination. The publications on MDR isolates were scarce.