Introduction: In realizing the promise of electronic health records, the needs to address the potential ethical issues are of paramount importance. Objectives: This research aims to determine the perception regarding the ethical issues in using the electronic health record among the medical staff of King Khalid General Hospital, Hafar Al-Batin, Saudi Arabia. Method: This research is quantitative-cross sectional approach. There are 43 medical record staffs who served as the participants. In determining the number of participants, the researcher used simple random sampling. A self-administered tool was used to collect the data. Ethical approval was obtained before data gathering. This research employed frequency and percentage for the demographic profile and weighted mean. In order to determine the differences, exist on the perception of the participants based on the tested variables, t-test was used for gender. Meanwhile, Analysis of Variance (ANOVA) was conducted to determine the differences in the department, level of education, and age. Results: The perception of the medical record staff about the ethical issues in the use of electronic health record is positive (x=3.68). Meanwhile, there is no significant difference on the department (Sig: 0.419; p-val. 0.5), age (Sig: 0.574; p-val. 0.5), level of education (Sig: 0.979; p-val. 0.5), and gender (Sig: 0.156; p-val. 0.5). Conclusion: The medical record staff in King Khalid General Hospital, Hafar Al-Batin, Saudi Arabia, have a positive perception regarding the ethical issues on electronic health records. As such, it can be used to improve more the practices in safeguarding the records. Moreover, this positive perception can address future ethical issues that may arise. Further, there are no significant differences in the department where these participants are deployed, the age, level of education, and gender.