Signet-ring cell carcinomas are malignant tumors that may affect the stomach and the colon, but extrahepatic bile duct localization is rare. Here we present a case (a 56-year-old Moroccan woman), without either pancreato-biliary mal-junction or liver disease. The patient had obstructive jaundice. Morphological studies by MRI and ERCP revealed a bile duct tumor obstructing the common bile duct and invading gallbladder and hepatic hilum. Pathological examination revealed a carcinoma containing signet-ring cells. The evolution was characterized by rapid disease progression; the patient died in about five months. The case of our patient is among the rare cases described in the mainly Asian literature, and the first case reported in North Africa.