Inflammatory bowel disease (IBD) is a major problem worldwide that can be categorized into two main disorders, Crohn’s Disease (CD) and Ulcerative Colitis (UC). IBD development is related to a multifactorial combination including environmental factors, intestinal microflora, pathological immune responses, and genetic influences [1, 2, 6] IBD can affect the complete GI tract, starting from the mouth to the anus [3]. Dental considerations regarding IBD oral manifestations and complications must be acknowledged by dentists to reduce morbidity, and mortality, and improve overall patient lifestyle. In this review, we will provide an overview of dental considerations and oral manifestations related to Inflammatory bowel disease.