SUBMIT YOUR RESEARCH
Saudi Journal of Pathology and Microbiology (SJPM)
Volume-4 | Issue-02 | 99-106
Original Research Article
Endometrial Findings in Abnormal Uterine Bleeding
Dr. K. Kasthuri Thilagam, Dr. M. Thenmozhi
Published : Feb. 28, 2019
DOI : 10.21276/sjpm.2019.4.2.9
Abstract
Background: Alteration in the hormone status either due to primary intrinsic ovarian abnormalities or secondary disturbances in the hypothalamo - Pituitary - ovarian axis results in AUB. The etiology of AUB is often related to anovulatory disturbances and ovulatory disturbances. However, there is a need to evaluate the endometrial changes specific for ovulatory and anovulatory causes of AUB at the histological level. This study was carried out to evaluate the histomorphological pattern of endometrium in Abnormal Uterine Bleeding. Methods: This cross sectional study was carried out among 100 women who were diagnosed with AUB in our tertiary care hospital between 2012 and 2014. Endometrial biopsy sample was taken on the third week of menstrual cycle. The samples received were carefully examined for the presence of mucus & large blood clots, and, if found were removed. One slide stained with conventional Haematoxylin & Eosin, second slide with Per iodic acid Schiff method and third slide was stained with Gomeri's method for reticulin stain. Results: A total of 100 cases were analyzed in this study and majority of the cases consisted of anovulatory disturbances (62%) followed by ovulatory disturbances (34%). While majority of the anovulatory cases were irregular proliferation (27%), majority of the ovulatory cases were deficient secretory state with co-ordinated delay (11%). Conclusion: In the modern era of minimally invasive surgical and diagnostic procedures, there is a growing need for the histopathologist to develop acumen for diagnosis of AUB. This study has extensively highlighted the variations in the endometrial presentation for an in depth analysis of AUB.
Scholars Middle East Publishers
Browse Journals
Payments
Publication Ethics
SUBMIT ARTICLE
Browse Journals
Payments
Publication Ethics
SUBMIT ARTICLE
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
© Copyright Scholars Middle East Publisher. All Rights Reserved.